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ICD-O-3-ONCOLOGY

WHO oncological topo + histo classification.

Definition

ICD-O-3 codes: Topography (C00-C97 aligned with ICD-10 chapter II), Morphology 4-digit + behaviour /0 benign /1 uncertain /2 in situ /3 malignant /6 metastatic, Grade 1-4. Updates: ICD-O-3.1 published WHO 2013, ICD-O-3.2 published 2020. Tools: ICD-O-3 Coding Companion (IARC), AERS Oncology Coding. Adoption: WHO/IARC cancer registries, NAACCR USA, IARC Globocan, France INCa.

Origin

ICD-O first edition published 1976 by WHO ; ICD-O-3 published 2000 ; revision 3.1 published 2013 ; revision 3.2 published 2020.

Example in context

A French cancer registry codes an Invasive ductal pancreatic adenocarcinoma in ICD-O-3: Topo C25.0 (head of pancreas) + Morpho 8500/3 (adenocarcinoma malignant).

Last updated: May 16, 2026